The hype around PRP (Platelet-Rich Plasma) has sparked controversy for several reasons, leading to the discussion of whether it’s worth getting PRP for hair loss or not. Personally, I’m of the opinion that PRP is overrated as a hair loss treatment. Below are some key factors contributing to my perspective.

The support for the effectiveness of PRP remains inconclusive. Certain studies suggest positive outcomes in specific applications. The overall consensus within the scientific community, however, is not universally robust. Skepticism arises due to the variability in study designs and inconsistent results across different contexts. 

A closer examination of this 2022 study reveals the limited effectiveness of PRP for AGA (Androgenetic Alopecia) patients. Shockingly, in five out of the seven categories measuring positive impacts, clinicians recorded less than a 50% probability of occurrence. Given PRP’s widespread popularity and hype, a success rate below the 50-50 mark is undeniably underwhelming.

2. Diverse Applications, Varied Efficacy

PRP is used in various medical and cosmetic applications. These include orthopedics, dermatology, and sports medicine. The broad scope of its application raises questions about its universal efficacy. The effectiveness of PRP may be more pronounced in specific conditions and less so in others, making it challenging to generalize its benefits.

3. Commercial Interests and Marketing

Some of the hype around PRP may be fueled by commercial interests and aggressive marketing rather than robust scientific evidence.  This is notably exemplified by Kim Kardashian and the infamous “vampire facial.”

The potential profitability of PRP treatments may lead to biased reporting and a tendency to emphasize positive outcomes while downplaying limitations or negative findings. 

4. PRP Application May Backfire

It’s crucial to note that the benefits of PRP may vary depending on the application. Yes, PRP has positive effects on skin rejuvenation by promoting collagen production and tissue repair. However, its efficacy in treating hair loss is a topic of ongoing debate. Some of the growth factors in PRP cause controlled skin fibrosis, and this mild scarring gives the skin a smoother appearance. The same growth factors in PRP may have adverse effects on hair follicles. Hair loss is often caused by scarring inflammation. The stimulation of fibrosis, or scarring, by these growth factors can lead to hair loss, a condition known as alopecia.

5. Placebo Effect and Patient Expectations

If PRP yields such inconsistent results and may even cause hair loss, what’s behind all those positive anecdotes you may be hearing? The placebo effect, where patients experience improvements due to their belief in the efficacy of a treatment, can influence perceptions of PRP’s effectiveness. There is a strong emphasis on positive anecdotes and testimonials, which may contribute to the placebo effect, creating an exaggerated perception of PRP’s benefits.

6. Lack of Standardization

Some may assume that the efficacy of PRP depends on the type of PRP machine used. However, the lack of standardized protocols for PRP preparation and administration is another point of concern. The variations in the concentration of platelets, the preparation methods, and application techniques contribute to inconsistent results. A more standardized approach could help better understand and replicate the outcomes of PRP treatments.

It’s Not Worth the Hype

The perceived overhyping of PRP is linked to the lack of a robust scientific consensus, diverse and sometimes inconsistent applications, commercial interests, the placebo effect, and the lack of standardization. As the field continues to evolve, ongoing research and critical evaluation will be essential to determine the actual benefits and limitations of PRP therapy. As it stands now, I think you should save your money for treatments that actually do work.

Frequently Asked Questions

What’s an alternative to PRP if PRP is not good for hair?

One alternative is growth factors. PRP contains factors that are good for hair and some that are actually harmful and can cause further hair loss. 

Growth factors are the good factors isolated from the rest of PRP. You get the benefits that you would be getting from PRP without the adverse effects.

References

Hetz, S.P., Martin, J. and Pototschnig, H. (2022) Patient satisfaction and clinical effects of platelet-rich plasma on pattern hair loss in male and female patients, Cureus. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534340/ (Accessed: 30 October 2023). 

WG;, M.M. (2018) Commentary on: Effect of use of platelet-rich plasma (PRP) in skin with intrinsic aging process, Aesthetic surgery journal. Available at: https://pubmed.ncbi.nlm.nih.gov/29126293/ (Accessed: 30 October 2023).